Mycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2

Mycobacterium tuberculosis (Mtb) employs multiple strategies to evade host immune responses and persist within macrophages. We have previously shown that the cell envelope-associated Mtb serine hydrolase, Hip1, prevents robust macrophage activation and dampens host pro-inflammatory responses, allowi...

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Bibliografiske detaljer
Main Authors: Naffin-Olivos, Jacqueline L., Georgieva, Maria, Goldfarb, Nathan, Madan-Lala, Ranjna, Dong, Lauren, Bizzell, Erica, Valinetz, Ethan, Brandt, Gabriel S., Yu, Sarah, Shabashvili, Daniil E., Ringe, Dagmar, Dunn, Ben M., Petsko, Gregory A., Rengarajan, Jyothi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022732/
https://ncbi.nlm.nih.gov/pubmed/24830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004132
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