Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c)

The Mycobacterium tuberculosis (Mtb) serine protease Hip1 (hydrolase important for pathogenesis; Rv2224c) promotes tuberculosis (TB) pathogenesis by impairing host immune responses through proteolysis of a protein substrate, Mtb GroEL2. The cell surface localization of Hip1 and its immunomodulatory...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Naffin-Olivos, Jacqueline L., Daab, Andrew, White, Andre, Goldfarb, Nathan E., Milne, Amy C., Liu, Dali, Baikovitz, Jacqueline, Dunn, Ben M., Rengarajan, Jyothi, Petsko, Gregory A., Ringe, Dagmar
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033327/
https://ncbi.nlm.nih.gov/pubmed/28346784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01066
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