Mycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2

Mycobacterium tuberculosis (Mtb) employs multiple strategies to evade host immune responses and persist within macrophages. We have previously shown that the cell envelope-associated Mtb serine hydrolase, Hip1, prevents robust macrophage activation and dampens host pro-inflammatory responses, allowi...

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Détails bibliographiques
Auteurs principaux: Naffin-Olivos, Jacqueline L., Georgieva, Maria, Goldfarb, Nathan, Madan-Lala, Ranjna, Dong, Lauren, Bizzell, Erica, Valinetz, Ethan, Brandt, Gabriel S., Yu, Sarah, Shabashvili, Daniil E., Ringe, Dagmar, Dunn, Ben M., Petsko, Gregory A., Rengarajan, Jyothi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022732/
https://ncbi.nlm.nih.gov/pubmed/24830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004132
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