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Inhibition of the Plasma-Membrane-Associated Serine Protease Cathepsin G by Mycobacterium tuberculosis Rv3364c Suppresses Caspase-1 and Pyroptosis in Macrophages

Tuberculosis is a disease associated with the infection of a great part of the world’s population and is responsible for the death of two to three million people annually. Mycobacterium tuberculosis infects macrophages and subverts its mechanisms of killing. The pathogen suppresses macrophage apopto...

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Détails bibliographiques
Auteurs principaux: Danelishvili, Lia, Everman, Jamie L., McNamara, Michael J., Bermudez, Luiz E.
Format: Artigo
Langue:Inglês
Publié: Frontiers Research Foundation 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257866/
https://ncbi.nlm.nih.gov/pubmed/22275911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00281
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