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Inhibition of the Plasma-Membrane-Associated Serine Protease Cathepsin G by Mycobacterium tuberculosis Rv3364c Suppresses Caspase-1 and Pyroptosis in Macrophages

Tuberculosis is a disease associated with the infection of a great part of the world’s population and is responsible for the death of two to three million people annually. Mycobacterium tuberculosis infects macrophages and subverts its mechanisms of killing. The pathogen suppresses macrophage apopto...

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Detalhes bibliográficos
Main Authors: Danelishvili, Lia, Everman, Jamie L., McNamara, Michael J., Bermudez, Luiz E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257866/
https://ncbi.nlm.nih.gov/pubmed/22275911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00281
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