Llwytho...

GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state

The HIV-1 restriction factor sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1) is a tetrameric protein that catalyzes the hydrolysis of all dNTPs to the deoxynucleoside and tripolyphosphate, which effectively depletes the dNTP substrates of HIV reverse transcriptase. Here, we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hansen, Erik C., Seamon, Kyle J., Cravens, Shannen L., Stivers, James T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020072/
https://ncbi.nlm.nih.gov/pubmed/24753578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401706111
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!