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Functional Production of a Soluble and Secreted Single-Chain Antibody by a Bacterial Secretion System
Single-chain variable fragments (scFvs) serve as an alternative to full-length monoclonal antibodies used in research and therapeutic and diagnostic applications. However, when recombinant scFvs are overexpressed in bacteria, they often form inclusion bodies and exhibit loss of function. To overcome...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019604/ https://ncbi.nlm.nih.gov/pubmed/24824752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097367 |
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