Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine

The development of effective adjuvant is the key factor to boost the immunogenicity of tumor cells as a tumor vaccine. In this study, we expressed membrane-bound granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-18 (IL-18) as adjuvants in tumor cells to stimulate immune respo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Chien-Chiao, Kuo, Kung-Kai, Cheng, Ta-Chun, Chuang, Chih-Hung, Kao, Chien-Han, Hsieh, Yuan-Chin, Cheng, Kuang-Hung, Wang, Jaw-Yuan, Cheng, Chiu-Min, Chen, Chien-Shu, Cheng, Tian-Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506079/
https://ncbi.nlm.nih.gov/pubmed/26186692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133470
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