Sulfonate-Containing Thiiranes as Selective Gelatinase Inhibitors

[Image: see text] Matrix metalloproteinases (MMPs) are important zinc-dependent endopeptidases. Two members of this family of enzymes called gelatinases (MMP-2 and MMP-9) have been implicated in a number of human diseases, including cancer, neurological and cardiovascular diseases, and inflammation,...

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Hauptverfasser: Testero, Sebastian A., Lee, Mijoon, Staran, Rachel T., Espahbodi, Mana, Llarrull, Leticia I., Toth, Marta, Mobashery, Shahriar, Chang, Mayland
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018095/
https://ncbi.nlm.nih.gov/pubmed/24900296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100254e
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