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Virus-Mediated shRNA Knockdown of Prodynorphin in the Rat Nucleus Accumbens Attenuates Depression-Like Behavior and Cocaine Locomotor Sensitization

Dynorphins, endogenous opioid peptides that arise from the precursor protein prodynorphin (Pdyn), are hypothesized to be involved in the regulation of mood states and the neuroplasticity associated with addiction. The current study tested the hypothesis that dynorphin in the nucleus accumbens (NAcc)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cohen, Ami, Whitfield, Timothy W., Kreifeldt, Max, Koebel, Pascale, Kieffer, Brigitte L., Contet, Candice, George, Olivier, Koob, George F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016270/
https://ncbi.nlm.nih.gov/pubmed/24816773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097216
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