A Genome Wide Association Study of Plasmodium falciparum Susceptibility to 22 Antimalarial Drugs in Kenya

BACKGROUND: Drug resistance remains a chief concern for malaria control. In order to determine the genetic markers of drug resistant parasites, we tested the genome-wide associations (GWA) of sequence-based genotypes from 35 Kenyan P. falciparum parasites with the activities of 22 antimalarial drugs...

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Auteurs principaux: Wendler, Jason P., Okombo, John, Amato, Roberto, Miotto, Olivo, Kiara, Steven M., Mwai, Leah, Pole, Lewa, O'Brien, John, Manske, Magnus, Alcock, Dan, Drury, Eleanor, Sanders, Mandy, Oyola, Samuel O., Malangone, Cinzia, Jyothi, Dushyanth, Miles, Alistair, Rockett, Kirk A., MacInnis, Bronwyn L., Marsh, Kevin, Bejon, Philip, Nzila, Alexis, Kwiatkowski, Dominic P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014544/
https://ncbi.nlm.nih.gov/pubmed/24809681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096486
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