Baseline In Vitro Activities of the Antimalarials Pyronaridine and Methylene Blue against Plasmodium falciparum Isolates from Kenya

We have analyzed the in vitro activities of pyronaridine and methylene blue against 59 Plasmodium falciparum isolates from Kenya in association with polymorphisms in Pfcrt (codon 76), Pfmdr1 (codon 86), and Pfnhe (full sequence). The median inhibitory concentrations that kill 50% of parasites were 1...

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Detalhes bibliográficos
Main Authors: Okombo, John, Kiara, Steven M., Mwai, Leah, Pole, Lewa, Ohuma, Eric, Ochola, Lynette Isabella, Nzila, Alexis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264213/
https://ncbi.nlm.nih.gov/pubmed/22123687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05454-11
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