Repeat Polymorphisms in the Low-Complexity Regions of Plasmodium falciparum ABC Transporters and Associations with In Vitro Antimalarial Responses

The Plasmodium falciparum genome is rich in regions of low amino acid complexity which evolve with few constraints on size. To explore the extent of diversity in these loci, we sequenced repeat regions in pfmdr1, pfmdr5, pfmdr6, pfmrp2, and the antigenic locus pfmsp8 in laboratory and cultured-adapt...

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Bibliografiska uppgifter
Huvudupphovsmän: Okombo, John, Abdi, Abdirahman I., Kiara, Steven M., Mwai, Leah, Pole, Lewa, Sutherland, Colin J., Nzila, Alexis, Ochola-Oyier, Lynette Isabella
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837885/
https://ncbi.nlm.nih.gov/pubmed/24080667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01465-13
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