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A Genome Wide Association Study of Plasmodium falciparum Susceptibility to 22 Antimalarial Drugs in Kenya

BACKGROUND: Drug resistance remains a chief concern for malaria control. In order to determine the genetic markers of drug resistant parasites, we tested the genome-wide associations (GWA) of sequence-based genotypes from 35 Kenyan P. falciparum parasites with the activities of 22 antimalarial drugs...

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Detalhes bibliográficos
Main Authors: Wendler, Jason P., Okombo, John, Amato, Roberto, Miotto, Olivo, Kiara, Steven M., Mwai, Leah, Pole, Lewa, O'Brien, John, Manske, Magnus, Alcock, Dan, Drury, Eleanor, Sanders, Mandy, Oyola, Samuel O., Malangone, Cinzia, Jyothi, Dushyanth, Miles, Alistair, Rockett, Kirk A., MacInnis, Bronwyn L., Marsh, Kevin, Bejon, Philip, Nzila, Alexis, Kwiatkowski, Dominic P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014544/
https://ncbi.nlm.nih.gov/pubmed/24809681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096486
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