Identification of HIV-1 Vif Regions Required for CBF-β Interaction and APOBEC3 Suppression

Human immunodeficiency virus type 1 (HIV-1) Vif requires core binding factor β (CBF-β) to degrade the host APOBEC3 restriction factors. Although a minimum domain and certain amino acids of HIV-1 Vif, including hydrophobic residues at the N-terminal, have been identified as critical sites for binding...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, Hong, Liu, Bin, Liu, Xin, Li, Zhaolong, Yu, Xiao-Fang, Zhang, Wenyan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014475/
https://ncbi.nlm.nih.gov/pubmed/24810617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095738
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items