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Identification of HIV-1 Vif Regions Required for CBF-β Interaction and APOBEC3 Suppression

Human immunodeficiency virus type 1 (HIV-1) Vif requires core binding factor β (CBF-β) to degrade the host APOBEC3 restriction factors. Although a minimum domain and certain amino acids of HIV-1 Vif, including hydrophobic residues at the N-terminal, have been identified as critical sites for binding...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Hong, Liu, Bin, Liu, Xin, Li, Zhaolong, Yu, Xiao-Fang, Zhang, Wenyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014475/
https://ncbi.nlm.nih.gov/pubmed/24810617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095738
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