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Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligase

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) Vif hijacks an E3 ligase to suppress natural APOBEC3 restriction factors, and core binding factor β (CBF-β) is required for this process. Although an extensive region of Vif spanning most of its N-terminus is known to be critical for binding wi...

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Bibliografske podrobnosti
izdano v:BMC Microbiol
Main Authors: Wang, Hong, Lv, Guoyue, Zhou, Xiaohong, Li, Zhaolong, Liu, Xin, Yu, Xiao-Fang, Zhang, Wenyan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265484/
https://ncbi.nlm.nih.gov/pubmed/25424878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-014-0290-7
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