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HIV-1 Vif N-terminal Motif is required for recruitment of Cul5 to Suppress APOBEC3
BACKGROUND: HIV-1 Vif promotes the degradation of host anti-retroviral factor family, APOBEC3 proteins via the recruitment of a multi-subunit E3 ubiquitin ligase complex. The complex is composed of a scaffold protein, Cullin 5 (Cul5), RING-box protein (Rbx), a SOCS box binding protein complex, Elong...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937519/ https://ncbi.nlm.nih.gov/pubmed/24422669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-4 |
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