Dispersed and Conserved Hydrophobic Residues of HIV-1 Vif Are Essential for CBFβ Recruitment and A3G Suppression

CBFβ was recently found to be a key regulator of the ability of human immunodeficiency virus type 1 (HIV-1) Vif to overcome host antiviral APOBEC3 proteins. However, the detailed molecular requirements for the Vif-CBFβ interaction are still not clear. Here, we mapped the minimum Vif domain required...

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Detalhes bibliográficos
Main Authors: Zhou, Xiaohong, Han, Xue, Zhao, Ke, Du, Juan, Evans, Sean L., Wang, Hong, Li, Peng, Zheng, Wenwen, Rui, Yajuan, Kang, Jian, Yu, Xiao-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958093/
https://ncbi.nlm.nih.gov/pubmed/24352440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03604-13
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