Evolutionarily Conserved Requirement for Core Binding Factor Beta in the Assembly of the Human Immunodeficiency Virus/Simian Immunodeficiency Virus Vif-Cullin 5-RING E3 Ubiquitin Ligase

The human immunodeficiency virus type 1 (HIV-1)-encoded virion infectivity factor (Vif) is required to inactivate the host restriction factor APOBEC3 by engaging Cullin 5 (Cul5)-RING ubiquitin ligase (CRL5). Core binding factor beta (CBF-β) is a novel regulator of Vif-CRL5 function; as yet, its mech...

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Detalhes bibliográficos
Main Authors: Han, Xue, Liang, Weizi, Hua, Deping, Zhou, Xiaohong, Du, Juan, Evans, Sean L., Gao, Qimeng, Wang, Hong, Viqueira, Rachel, Wei, Wei, Zhang, Wenyan, Yu, Xiao-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957933/
https://ncbi.nlm.nih.gov/pubmed/24390335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03833-13
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