Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen

Simian virus 40 (SV40) large tumor antigen (LT) triggers oncogenic transformation by inhibition of key tumor suppressor proteins, including p53 and members of the retinoblastoma family. In addition, SV40 transformation requires binding of LT to Cullin 7 (CUL7), a core component of Cullin-RING E3 ubi...

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Detalhes bibliográficos
Main Authors: Hartmann, Thomas, Xu, Xinsong, Kronast, Mira, Muehlich, Susanne, Meyer, Kathleen, Zimmermann, Wolfgang, Hurwitz, Jerard, Pan, Zhen-Qiang, Engelhardt, Stefan, Sarikas, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948260/
https://ncbi.nlm.nih.gov/pubmed/24550499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401556111
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