Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signalling()

Dysfunctional regulation of signalling pathways downstream of the insulin receptor plays a pivotal role in the pathogenesis of insulin resistance and type 2 diabetes. In this study we report both in vitro and in vivo experimental evidence for a role of Cullin-RING E3 ubiquitin ligase 7 (CRL7) in the...

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Détails bibliographiques
Auteurs principaux: Scheufele, Florian, Wolf, Benjamin, Kruse, Michael, Hartmann, Thomas, Lempart, Justine, Mühlich, Susanne, Pfeiffer, Andreas F. H., Field, Loren J., Charron, Maureen J., Pan, Zhen-Qiang, Engelhardt, Stefan, Sarikas, Antonio
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901049/
https://ncbi.nlm.nih.gov/pubmed/24219910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.11.005
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