Distinct Determinants in HIV-1 Vif and Human APOBEC3 Proteins Are Required for the Suppression of Diverse Host Anti-Viral Proteins

BACKGROUND: APOBEC3G (A3G) and related cytidine deaminases of the APOBEC3 family of proteins are potent inhibitors of many retroviruses, including HIV-1. Formation of infectious HIV-1 requires the suppression of multiple cytidine deaminases by Vif. HIV-1 Vif suppresses various APOBEC3 proteins throu...

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Main Authors: Zhang, Wenyan, Chen, Gongying, Niewiadomska, Anna Maria, Xu, Rongzhen, Yu, Xiao-Fang
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597746/
https://ncbi.nlm.nih.gov/pubmed/19088851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003963
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