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Improved Normalization of Systematic Biases Affecting Ion Current Measurements in Label-free Proteomics Data

Normalization is an important step in the analysis of quantitative proteomics data. If this step is ignored, systematic biases can lead to incorrect assumptions about regulation. Most statistical procedures for normalizing proteomics data have been borrowed from genomics where their development has...

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Main Authors: Rudnick, Paul A., Wang, Xia, Yan, Xinjian, Sedransk, Nell, Stein, Stephen E.
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014289/
https://ncbi.nlm.nih.gov/pubmed/24563535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.030593
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