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Normalization Approaches for Removing Systematic Biases Associated with Mass Spectrometry and Label-Free Proteomics

Central tendency, linear regression, locally weighted regression, and quantile techniques were investigated for normalization of peptide abundance measurements obtained from high-throughput liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry (LC-FTICR MS). Arbitrary abu...

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Detalhes bibliográficos
Main Authors: Callister, Stephen J., Barry, Richard C., Adkins, Joshua N., Johnson, Ethan T., Qian, Weijun, Webb-Robertson, Bobbie-Jo M., Smith, Richard D., Lipton, Mary S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1992440/
https://ncbi.nlm.nih.gov/pubmed/16457593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr050300l
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