Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline: APPLICATION TO PROTEIN ACETYLATION AND PHOSPHORYLATION

Despite advances in metabolic and postmetabolic labeling methods for quantitative proteomics, there remains a need for improved label-free approaches. This need is particularly pressing for workflows that incorporate affinity enrichment at the peptide level, where isobaric chemical labels such as is...

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Detalhes bibliográficos
Main Authors: Schilling, Birgit, Rardin, Matthew J., MacLean, Brendan X., Zawadzka, Anna M., Frewen, Barbara E., Cusack, Michael P., Sorensen, Dylan J., Bereman, Michael S., Jing, Enxuan, Wu, Christine C., Verdin, Eric, Kahn, C. Ronald, MacCoss, Michael J., Gibson, Bradford W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418851/
https://ncbi.nlm.nih.gov/pubmed/22454539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.017707
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