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Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

Protein quantification without isotopic labels has been a long-standing interest in the proteomics field. However, accurate and robust proteome-wide quantification with label-free approaches remains a challenge. We developed a new intensity determination and normalization procedure called MaxLFQ tha...

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Autors principals: Cox, Jürgen, Hein, Marco Y., Luber, Christian A., Paron, Igor, Nagaraj, Nagarjuna, Mann, Matthias
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159666/
https://ncbi.nlm.nih.gov/pubmed/24942700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.031591
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