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Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging

The biological process of aging is believed to be the result of an accumulation of cellular damage to biomolecules. Although there are numerous studies addressing mutation frequencies, morphological or transcriptional changes in aging mammalian tissues, few have measured global changes at the protei...

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Autors principals: Walther, Dirk M., Mann, Matthias
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033683/
https://ncbi.nlm.nih.gov/pubmed/21048193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.004523
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