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A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor

The cellular prion protein, PrP(C), is a glycosylphosphatidylinositol-anchored protein, abundant in lipid rafts and highly expressed in the brain. While PrP(C) is much studied for its involvement under its abnormal PrP(Sc) isoform in Transmissible Spongiform Encephalopathies, its physiological role...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hernandez-Rapp, Julia, Martin-Lannerée, Séverine, Hirsch, Théo Z., Pradines, Elodie, Alleaume-Butaux, Aurélie, Schneider, Benoît, Baudry, Anne, Launay, Jean-Marie, Mouillet-Richard, Sophie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013941/
https://ncbi.nlm.nih.gov/pubmed/24810941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04881
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