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A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor

The cellular prion protein, PrP(C), is a glycosylphosphatidylinositol-anchored protein, abundant in lipid rafts and highly expressed in the brain. While PrP(C) is much studied for its involvement under its abnormal PrP(Sc) isoform in Transmissible Spongiform Encephalopathies, its physiological role...

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Detalhes bibliográficos
Main Authors: Hernandez-Rapp, Julia, Martin-Lannerée, Séverine, Hirsch, Théo Z., Pradines, Elodie, Alleaume-Butaux, Aurélie, Schneider, Benoît, Baudry, Anne, Launay, Jean-Marie, Mouillet-Richard, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013941/
https://ncbi.nlm.nih.gov/pubmed/24810941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04881
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