A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor

The cellular prion protein, PrP(C), is a glycosylphosphatidylinositol-anchored protein, abundant in lipid rafts and highly expressed in the brain. While PrP(C) is much studied for its involvement under its abnormal PrP(Sc) isoform in Transmissible Spongiform Encephalopathies, its physiological role...

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Autors principals: Hernandez-Rapp, Julia, Martin-Lannerée, Séverine, Hirsch, Théo Z., Pradines, Elodie, Alleaume-Butaux, Aurélie, Schneider, Benoît, Baudry, Anne, Launay, Jean-Marie, Mouillet-Richard, Sophie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013941/
https://ncbi.nlm.nih.gov/pubmed/24810941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04881
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