A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts

E2F-1, a key transcription factor necessary for cell growth, DNA repair and differentiation, is an attractive target for development of useful anticancer drugs in tumors that are E2F “oncogene addicted”. A peptide, isolated from phage clones, based on its binding to an E2F-1 consensus sequence, was...

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Dades bibliogràfiques
Autors principals: Xie, Xiaoqi, Bansal, Nitu, Shaik, Tazeem, Kerrigan, John E., Minko, Tamara, Garbuzenko, Olga, Abali, Emine Ercikan, Johnson-Farley, Nadine, Banerjee, Debabrata, Scotto, Kathleen W., Bertino, Joseph R
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011592/
https://ncbi.nlm.nih.gov/pubmed/24658650
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