Antitumor and modeling studies of a penetratin-peptide that targets E2F-1 in small cell lung cancer

E2F-1, a key transcription factor necessary for cell growth, DNA repair, and differentiation, is an attractive target for development of anticancer drugs in tumors that are E2F “oncogene addicted”. We identified a peptide isolated from phage clones that bound tightly to the E2F-1 promoter consensus...

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Hlavní autoři: Xie, Xiaoqi, Kerrigan, John E, Minko, Tamara, Garbuzenko, Olga, Lee, Kuo-Chieh, Scarborough, Alex, Abali, Emine Ercikan, Budak-Alpdogan, Tulin, Johnson-Farley, Nadine, Banerjee, Debabrata, Scotto, Kathleen W, Bertino, Joseph R
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841214/
https://ncbi.nlm.nih.gov/pubmed/23792570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25184
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