Modeling and antitumor studies of a modified L–penetratin peptide targeting E2F in lung cancer and prostate cancer

E2F1-3a overexpression due to amplification or to mutation or loss of the retinoblastoma gene, induces genes involved in DNA synthesis and leads to abnormal cellular proliferation, tumor growth, and invasion. Therefore, inhibiting the overexpression of one or more of these activating E2Fs is a recog...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shaik, Tazeem, Rather, Gulam M., Bansal, Nitu, Minko, Tamara, Garbuzenko, Olga, Szekely, Zoltan, Abali, Emine E., Banerjee, Debabrata, Kerrigan, John E., Scotto, Kathleen W., Bertino, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161789/
https://ncbi.nlm.nih.gov/pubmed/30279956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26064
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