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A Novel Antibody-Toxin Conjugate to Treat Mantle Cell Lymphoma

Matriptase is a transmembrane serine protease, synthesized as an inactive single-chain zymogen on the endoplasmic reticulum and transported to the plasma membrane. Matriptase is activated in different epithelial and some B-cell malignancies and changes its conformation and activity is inhibited main...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Rather, Gulam M., Lin, Siang-Yo, Lin, Hongxia, Szekely, Zoltan, Bertino, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467949/
https://ncbi.nlm.nih.gov/pubmed/31024856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00258
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