Activated matriptase as a target to treat breast cancer with a drug conjugate

The antitumor effects of a novel antibody drug conjugate (ADC) was tested against human solid tumor cell lines and against human triple negative breast cancer (TNBC) xenografts in immunosuppressed mice. The ADC targeting activated matriptase of tumor cells was synthesized by using the potent anti-tu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rather, Gulam M., Lin, Siang-Yo, Lin, Hongxia, Banach-Petrosky, Whitney, Hirshfield, Kim M., Lin, Chen-Yong, Johnson, Michael D., Szekely, Zoltan, Bertino, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995259/
https://ncbi.nlm.nih.gov/pubmed/29899836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25414
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados