Llwytho...

p53-mediated heterochromatin reorganization regulates its cell fate decisions

p53 is a major sensor of cellular stresses, and its activation influences cell fate decisions. We identified SUV39H1, a histone code ‘writer’ responsible for the histone H3 Lys9 trimethylation (H3K9me3) mark for ‘closed’ chromatin conformation, as a target of p53 repression. SUV39H1 downregulation w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mungamuri, Sathish Kumar, Benson, Erica Kay, Wang, Shaomeng, Gu, Wei, Lee, Sam W, Aaronson, Stuart A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009975/
https://ncbi.nlm.nih.gov/pubmed/22466965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2271
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