Cell fate decision mediated by p53 pulses

The tumor suppressor p53 plays a crucial role in cellular response to various stresses. Recent experiments have shown that p53 level exhibits a series of pulses after DNA damage caused by ionizing radiation (IR). However, how the p53 pulses govern cell survival and death remains unclear. Here, we de...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Xiao-Peng, Liu, Feng, Cheng, Zhang, Wang, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Physical Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710988/
https://ncbi.nlm.nih.gov/pubmed/19617533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813088106
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