The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise

door Mandinova, Anna, Lee, Sam W.
Gepubliceerd in 2011

Losing p53 loosens up ER-stress

door Byun, Sanguine, Namba, Takushi, Lee, Sam W.
Gepubliceerd in Aging (Albany NY) (2015)

Comparative Analysis of P73 and P53 Regulation and Effector Functions

door Fang, Li, Lee, Sam W., Aaronson, Stuart A.
Gepubliceerd in 1999

Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence

door Benson, Erica K., Lee, Sam W., Aaronson, Stuart A.
Gepubliceerd in 2010

A putative role for Discoidin Domain Receptor 1 in cancer chemoresistance

door Ambrogio, Chiara, Darbo, Elodie, Lee, Sam W., Santamaría, David
Gepubliceerd in Cell Adh Migr (2018)

Loss of Wip1 Sensitizes Cells to Stress- and DNA Damage-induced Apoptosis

door Xia, Yun, Ongusaha, Pat, Lee, Sam W., Liou, Yih-Cherng
Gepubliceerd in 2009

MTA1-Mediated Transcriptional Repression of BRCA1 Tumor Suppressor Gene

door Molli, Poonam R., Singh, Rajesh R., Lee, Sam W., Kumar, Rakesh
Gepubliceerd in 2007

Emerging roles of p53 and other tumour-suppressor genes in immune regulation

door Muñoz-Fontela, César, Mandinova, Anna, Aaronson, Stuart A., Lee, Sam W.
Gepubliceerd in Nat Rev Immunol (2016)

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53

door Sugrue, Mary M., Shin, Deug Y., Lee, Sam W., Aaronson, Stuart A.
Gepubliceerd in 1997

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

door Fang, Li, Li, Guangnan, Liu, Guizhong, Lee, Sam W., Aaronson, Stuart A.
Gepubliceerd in 2001

Novel Oxidative Stress-responsive Gene ERS25 Functions as a Regulator of the Heat-shock and Cell Death Response

door Hwang, Sun Ok, Boswell, Sarah A., Seo, Jeong-Sun, Lee, Sam W.
Gepubliceerd in 2008

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes

door Ouchi, Toru, Lee, Sam W., Ouchi, Mutsuko, Aaronson, Stuart A., Horvath, Curt M.
Gepubliceerd in 2000

Influence of Induced Reactive Oxygen Species in p53-Mediated Cell Fate Decisions

door Macip, Salvador, Igarashi, Makoto, Berggren, Petra, Yu, Jian, Lee, Sam W., Aaronson, Stuart A.
Gepubliceerd in 2003

Hzf, a key modulator of p53 mediated transcription, functions as a critical determinant of cell survival and death upon genotoxic stress

door Das, Sanjeev, Raj, Lakshmi, Zhao, Bo, Bernstein, Alan, Aaronson, Stuart A., Lee, Sam W.
Gepubliceerd in 2007

DDR1 Receptor Tyrosine Kinase Promotes Prosurvival Pathway through Notch1 Activation

door Kim, Hyung-Gu, Hwang, So-Young, Aaronson, Stuart A., Mandinova, Anna, Lee, Sam W.
Gepubliceerd in 2011

Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors

door Canning, Peter, Tan, Li, Chu, Kiki, Lee, Sam W., Gray, Nathanael S., Bullock, Alex N.
Gepubliceerd in 2014

DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.

door Kim, Hyung-Gu, Hwang, So Young, Aaronson, Stuart A., Mandinova, Anna, Lee, Sam W.
Gepubliceerd in J Biol Chem (2017)

Effects of p21 deletion in mouse models of premature aging

door Benson, Erica K., Zhao, Bo, Sassoon, David A., Lee, Sam W., Aaronson, Stuart A.
Gepubliceerd in Cell Cycle (2009)

Withdrawal: DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.

door Kim, Hyung-Gu, Hwang, So-Young, Aaronson, Stuart A., Mandinova, Anna, Lee, Sam W.
Gepubliceerd in J Biol Chem (2019)

Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53

door Lee, Sam W., Fang, Li, Igarashi, Makoto, Ouchi, Toru, Lu, Kun Ping, Aaronson, Stuart A.
Gepubliceerd in 2000