Influence of Induced Reactive Oxygen Species in p53-Mediated Cell Fate Decisions

The p53 tumor suppressor gene can induce either apoptosis or a permanent growth arrest (also termed senescence) phenotype in response to cellular stresses. We show that the increase in intracellular reactive oxygen species (ROS) associated with the magnitude of p53 protein expression correlated with...

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Main Authors: Macip, Salvador, Igarashi, Makoto, Berggren, Petra, Yu, Jian, Lee, Sam W., Aaronson, Stuart A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Cell Growth and Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC262651/
https://ncbi.nlm.nih.gov/pubmed/14612402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8576-8585.2003
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