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Influence of Induced Reactive Oxygen Species in p53-Mediated Cell Fate Decisions

The p53 tumor suppressor gene can induce either apoptosis or a permanent growth arrest (also termed senescence) phenotype in response to cellular stresses. We show that the increase in intracellular reactive oxygen species (ROS) associated with the magnitude of p53 protein expression correlated with...

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Detalhes bibliográficos
Main Authors: Macip, Salvador, Igarashi, Makoto, Berggren, Petra, Yu, Jian, Lee, Sam W., Aaronson, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262651/
https://ncbi.nlm.nih.gov/pubmed/14612402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8576-8585.2003
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