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Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes

Most of the activities of IFN-γ are the result of STAT1-mediated transcriptional responses. In this study, we show that the BRCA1 tumor suppressor acts in concert with STAT1 to differentially activate transcription of a subset of IFN-γ target genes and mediates growth inhibition by this cytokine. Af...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ouchi, Toru, Lee, Sam W., Ouchi, Mutsuko, Aaronson, Stuart A., Horvath, Curt M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC25807/
https://ncbi.nlm.nih.gov/pubmed/10792030
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