Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes

Most of the activities of IFN-γ are the result of STAT1-mediated transcriptional responses. In this study, we show that the BRCA1 tumor suppressor acts in concert with STAT1 to differentially activate transcription of a subset of IFN-γ target genes and mediates growth inhibition by this cytokine. Af...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ouchi, Toru, Lee, Sam W., Ouchi, Mutsuko, Aaronson, Stuart A., Horvath, Curt M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.080469697
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