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Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels
BACKGROUND AND PURPOSE: Evodiamine, a racemic quinazolinocarboline alkaloid isolated from the traditional Chinese medicine Evodiae fructus, has been reported to act as an agonist of the transient receptor potential vanilloid type-1 (TRPV1) cation channel both in vitro and in vivo. Evodiamine is stru...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009003/ https://ncbi.nlm.nih.gov/pubmed/23902373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12320 |
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