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The anti‐inflammatory mediator palmitoylethanolamide enhances the levels of 2‐arachidonoyl‐glycerol and potentiates its actions at TRPV1 cation channels

BACKGROUND AND PURPOSE: Palmitoylethanolamide (PEA) is an endogenous congener of anandamide and potentiates its actions at cannabinoid CB (1) and CB (2) receptors, and at transient receptor potential vanilloid type‐1 (TRPV1) channels. The other endocannabinoid, 2‐arachidonoylglycerol (2‐AG), was rec...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Petrosino, Stefania, Schiano Moriello, Aniello, Cerrato, Santiago, Fusco, Mariella, Puigdemont, Anna, De Petrocellis, Luciano, Di Marzo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338153/
https://ncbi.nlm.nih.gov/pubmed/25598150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13084
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