The anti‐inflammatory mediator palmitoylethanolamide enhances the levels of 2‐arachidonoyl‐glycerol and potentiates its actions at TRPV1 cation channels

BACKGROUND AND PURPOSE: Palmitoylethanolamide (PEA) is an endogenous congener of anandamide and potentiates its actions at cannabinoid CB (1) and CB (2) receptors, and at transient receptor potential vanilloid type‐1 (TRPV1) channels. The other endocannabinoid, 2‐arachidonoylglycerol (2‐AG), was rec...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Petrosino, Stefania, Schiano Moriello, Aniello, Cerrato, Santiago, Fusco, Mariella, Puigdemont, Anna, De Petrocellis, Luciano, Di Marzo, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
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Themed Section: Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338153/
https://ncbi.nlm.nih.gov/pubmed/25598150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13084
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