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Reshaping Antibody Diversity
Unlike humans or mice, some species have limited genome encoded combinatorial diversity potential, yet mount a robust antibody response. Cows are unusual in having exceptionally long CDR H3 loops and few V-regions, but the mechanism for creating diversity is not understood. Deep sequencing revealed...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007204/ https://ncbi.nlm.nih.gov/pubmed/23746848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.049 |
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