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Fatty acids increase neuronal hypertrophy of Pten knockdown neurons
Phosphatase and tensin homolog (Pten) catalyzes the reverse reaction of PI3K by dephosphorylating PIP3 to PIP2. This negatively regulates downstream Akt/mTOR/S6 signaling resulting in decreased cellular growth and proliferation. Co-injection of a lentivirus knocking Pten down with a control lentivir...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006057/ https://ncbi.nlm.nih.gov/pubmed/24795563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00030 |
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