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Rapamycin Prevents, but does not Reverse, Aberrant Migration in Pten Knockout Neurons
Phosphatase and tensin homolog (PTEN) is a major negative regulator of the Akt/mammalian target of rapamycin (mTor) pathway. Mutations in PTEN have been found in a subset of individuals with autism and macrocephaly. Further, focal cortical dysplasia (FCD) has been observed in patients with PTEN muta...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5409093/ https://ncbi.nlm.nih.gov/pubmed/26992888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.03.010 |
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