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Hyperactivity of Newborn Pten Knock-out Neurons Results from Increased Excitatory Synaptic Drive
Developing neurons must regulate morphology, intrinsic excitability, and synaptogenesis to form neural circuits. When these processes go awry, disorders, including autism spectrum disorder (ASD) or epilepsy, may result. The phosphatase Pten is mutated in some patients having ASD and seizures, sugges...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300333/ https://ncbi.nlm.nih.gov/pubmed/25609613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3144-14.2015 |
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