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Pten Knockdown In Vivo Increases Excitatory Drive onto Dentate Granule Cells

Some cases of autism spectrum disorder have mutations in the lipid phosphatase, phosphatase and tensin homolog on chromosome 10 (Pten). Tissue specific deletion of Pten in the hippocampus and cortex of mice causes anatomical and behavioral abnormalities similar to human autism. However, the impact o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Luikart, Bryan W., Schnell, Eric, Washburn, Eric K., Bensen, AeSoon L., Tovar, Kenneth R., Westbrook, Gary L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113533/
https://ncbi.nlm.nih.gov/pubmed/21411674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0061-11.2011
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