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Pten Knockdown In Vivo Increases Excitatory Drive onto Dentate Granule Cells

Some cases of autism spectrum disorder have mutations in the lipid phosphatase, phosphatase and tensin homolog on chromosome 10 (Pten). Tissue specific deletion of Pten in the hippocampus and cortex of mice causes anatomical and behavioral abnormalities similar to human autism. However, the impact o...

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Bibliografische gegevens
Hoofdauteurs: Luikart, Bryan W., Schnell, Eric, Washburn, Eric K., Bensen, AeSoon L., Tovar, Kenneth R., Westbrook, Gary L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113533/
https://ncbi.nlm.nih.gov/pubmed/21411674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0061-11.2011
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